Conditions
4 min read
December 15, 2022
Symptoms of iron deficiency

Symptoms of iron deficiency

Iron deficiency can affect far more than energy levels. Because iron is essential for neurotransmitter production, thyroid hormone activity, oxygen transport, and cellular metabolism, low levels can present as a wide range of physical, cognitive, and emotional symptoms—often before anemia is formally diagnosed.

How many of the following symptoms for iron deficiency do you have?

  • Non-Physical Symptoms
  • Anxiety
  • Cognitive dysfunction
  • Dizziness
  • Fatigue
  • Headaches
  • Lowered attention
  • Light-headedness
  • Mood swings
  • Post-partum depression

Physical:

  • Atrophy or enlargement of the taste buds
  • Compromised immune function
  • Hair loss
  • Koilonychia (Brittle, spoon-shaped nails)
  • Leg cramps / heavy legs
  • Lowered body temperature
  • Mouth sores
  • Pale skin complexion
  • Palpitations
  • Poor thyroid function
  • Skin problems
  • Shortness of breath
  • Swollen tongue
  • Restless legs
  • Pregnancy complications

Here are some of the mechanisms behind the above symptoms:

Iron is required for tryptophan hydroxylase activity, this enzyme converts tryptophan to 5HTP, the precursor for serotonin – the chemical brain messenger responsible for our happiness. Therefore with inadequate iron levels, serotonin production will be reduced.

Iron is also needed for tyrosine hydroxylase, this enzyme is essential for the production of dopamine – the chemical brain messenger that is responsible for our drive and motivation.

Iron is essential for the intracellular reception of T3. This reduces the activity of the main thyroid hormone thus lowering metabolism, energy, whilst leading to hair loss and other related factors.

Iron is required to make hemoglobulin. Hemoglobulin helps carry oxygen within the blood to tissues, an integral part of energy production. If iron is low, the body’s ability to produce energy is hindered therefore increasing the likelihood for fatigue. This same mechanism leads to reduced oxygen availability to the brain giving reason as to why headaches are also linked to iron deficiency.

The paling of the skin and inside of the eyelids is due to less hemoglobulin within the blood, as hemoglobulin gives blood its red pigmentation.

Reduced hemoglobulin levels result in less oxygen within the body. As a compensatory mechanism, the body will start to increase breathing and heart rate in hope to get more oxygen, thus leading to a shortness of breath and increased heart palpitations.

Next news

Globally, more than 50% of all people are infected [8], with the prevalence of escalating with age. [9]

Helicobacter Pylori is a gram-negative bacterium that colonises within the human gastrointestinal tract (this includes the mouth).

Symptoms:

  • Belching
  • Nausea
  • Vomiting
  • Difficulty swallowing
  • Abdominal discomfort
  • Upper abdominal bloating
  • Decreased appetite
  • Peptic ulcers
  • Bad breath
  • Heartburn
  • Reoccurring oral plaque
  • Gingivitis
  • Tooth cavities

Risks:

  • H. Pylori infection is the main cause of chronic gastritis, with an infection rate between 80%-95% in sufferers. [7]
  • It is present in almost all cases of duodenal ulcers and most cases of gastric ulcer [10] with as many as 90% of individuals with ulcers being infected.
  • H. Pylori is a significant contributing factor for the risk of gastric cancers.
  • H. Pylori burrows deep within parietal cells (cells that secrete stomach acid), not only does this make it harder to eradicate, but this also leads to unique symptoms within the host. One factor being hypochlorhydria (low levels of stomach acid secreted within the body); this prevents the host from sterilising bacteria in food, reduces the ability to obtain nutrients desired from food and the inability to assimilate certain key minerals, such as zinc or iron.
  • Reduced intrinsic factor (IF) production is also likely for individuals suffering from a H. Pylori infection. IF is essential to bind with vitamin B12, preventing further breakdown from stomach acid along with attaching to the surface of the ileum to allow for absorption of B12 into the body.
  • H. Pylori can also block vitamin C absorption, thus compounding to the amount of oxidative damage inflicted onto the body.
  • H. Pylori infection augments the gastric mucosal damage induced by NSAIDs.
  • H. Pylori antagonises Aspirin-induced delayed ulcer healing due to suppression of acid secretion by the enhancement of PGE2 possibly derived by COX2 expression.
  • Benefits:
    Due to the nature of the parasite being a gram-negative bacteria, it shifts the immune system more towards a Th1 mediated response as opposed to Th2 – this can reduce the severity of allergies, asthma and other humeral/mucosal reactions.

Benefits:

Due to the nature of the parasite being a gram-negative bacteria, it shifts the immune system more towards a Th1 mediated response as opposed to Th2 – this can reduce the severity of allergies, asthma and other humeral/mucosal reactions.

References:

  1. Morales-Espinosa R, et al., Oral Microbiol Immunol. 2009
  2. Nguyen AM, et al., Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995
  3. Miyabayashi H, et al., Helicobacter. 2000
  4. Gebara EC, et al., J Clin Periodontol. 2006
  5. Dye BA, et al., Am J Public Health. 2002
  6. Eskandari A, et al. Med Oral Patol Oral Cir Bucal.
  7. Abro AH, et al. J Ayub Med Coll Abbottabad. 2011
  8. Saudi J Gastroenterol. 2014
  9. J Gastrointestin Liver Dis. 2011
  10. J Gastroenterol Hepatol. 2011
  11. Surveillance of Helicobacter pylori antibiotic resistance in England and Wales; Public Health England, 2008
  12. Jernberg, C, et al. 2010
Gut Health
6 min read
H Pylori: 50% globally infected
H Pylori: 50% globally infected
H. pylori disrupts stomach acid production, damages the gastric lining, and interferes with key nutrients such as B12, iron, zinc, and vitamin C. Although it may modulate immune balance by shifting responses toward Th1, its long-term risks to digestive, immune, and metabolic health are significant.
December 10, 2022

Trauma can lead to long lasting adaptive mechanisms to protect the individual from repeated exposure, usually these evolutionary defensive behavioural patterns continue later in life despite not being coherent to current day stressors. ⁣

This can lead to distorted situational awareness, disconnecting ones responses and actions from perceived ‘normative’ behaviour.⁣

Highly sensitive triggers may be running in the subconscious mind unknowingly to the individual.⁣

Studies show the adaptive response from trauma can extend over 14 generations. This is a huge component contributing to dysfunctional community syndrome and further stigmatisation.⁣

The following are common factors in trans-generational trauma:⁣

  • Accidental’ epidemics⁣
  • Massacres⁣
  • Starvations⁣
  • War⁣
  • Slavery ⁣
  • The removal of people to reserves ⁣

Below are examples of traumatic events:⁣

  • African Slavery⁣
  • The Holodomor⁣
  • The Holocaust⁣
  • World War 1⁣
  • World War 2⁣
  • Dutch Hunger Winter⁣
  • Ritualistic Abuse⁣
  • Aboriginal Australian Lineage⁣
  • Childhood sexual abuse ⁣
  • Middle Eastern War⁣

Do you think trans-generational trauma has impacted you in any way?

Mental Health
6 min read
Trans-generational trauma
Trans-generational trauma
Trans-generational trauma can quietly affect awareness, emotional regulation, and resilience. Recognising its influence may be a first step toward understanding inherited patterns and restoring agency, safety, and connection.
December 10, 2022

Depression is a complex disease with multiple contributing factors. The diagnostic criteria for depression include:

  • Depressed or irritable mood
  • Decreased interest in pleasurable activities and ability to experience pleasure
  • Significant weight gain or loss (>5% change in a month)
  • Insomnia or hypersomnia
  • Psychomotor agitation or retardation
  • Fatigue or loss of energy
  • Feelings of worthlessness or excessive guilt
  • Diminished ability to think or concentrate
  • Recurrent thoughts of death or suicide
    (Berton O, et al. Nat Rev Neurosci. 2006)

Chances are that you have felt several of the above criteria but yet you may not have associated it with depression.

This is because depression is a broad term that may affect one person differently to the next, along with having a diverse range of possible causations.

Below is a list of some of the factors that can lead to depression and apathy:

  • Trauma
  • PTSD
  • Abuse
  • Post-natal depression
  • Adverse childhood exposure
  • Lack of safety
  • Economic struggles
  • Autoimmunity
  • Social isolation
  • Heartbreak
  • Social media
  • Lack of purpose
  • S.A.D – Seasonal Affective Disorder (Vitamin D deficiency)
  • Mold exposure
  • Anaemia
  • Sex hormone imbalances (Low/high oestrogen, low testosterone)
  • Hypo/hyper thyroidism
  • Stress
  • Pain
  • Chronic illness
  • Genetic traits
  • Methylation issues
  • Heavy metal toxicity
  • Parasites
  • Nutrient deficiencies (B6, etc)
  • Nutrient excess
  • Artificial light exposure
  • Poor sleep
  • Mitochondrial dysfunctions
  • Poor gut health
  • Gut/brain axis inflammation
  • Cytokine model of depression
  • Medication
  • Loss of a loved one
  • Divorce
  • Substance abuse
  • Neurotransmitter imbalances
  • Lyme
  • Toxic and ambivalent relationships

Each reason, being so unique, may require a completely different approach for therapy from the next.

This reverberates a quote of William Osler, stating ‘It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has’. Unfortunately, society generally neglects the beauty of individuality whilst overlooking the crucial interplay and synergy from the multifactorial systems essential for optimal function within our body.

Mental Health
6 min read
The diversity of depression
The diversity of depression
Depression can arise from trauma, physiology, lifestyle, environment, or biochemical imbalance. Because no two cases are the same, effective care depends on understanding the individual—not just the diagnosis.
December 10, 2022
Clarity, confidence, and real results start with one conversation. Let’s map your next chapter — together.