H Pylori: 50% globally infected

You are only as ‘strong’ as your weakest link

Our body is a complex yet beautiful organism that we barely scrape the surface when it comes to an understanding of how we work.

What we do know is that every system within our body is interdependent on one another. It works and flows synergistically and has a bidirectional relationship.

We often prioritise aesthetics whilst neglecting other systems, only paying attention to them when it is too late and hardship, dysfunction, or disease has manifested as a consequence.

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The following systems are what need respect, nurture, and care:

• Muscular System
• Structural
• Endocrinological
• Neurological
• Gastro-Intestinal
• Microbial
• Cardiovascular System
• Pulmonary System
• Immunological
• Biotransformation
• Lymphatic System
• Psychological
• Emotional
• Environmental
• Spiritual

The effectiveness of Vitamin B6 in the treatment of PMS dates back over 40 years. Results were noted, such as:

• ‘Significant decreases in all symptoms’ (1)
• 70% reporting good or partial response’ (2)
• ‘Improvement in 63% of patients on pyridoxine’ (3)

The dose used within these studies ranged from 40-200mg (with a possible risk of toxicity at 200mg).

Only one patient of the 940 participating in these trials indicated the presence of any side effects that could be attributed to the neuropathy associated with pyridoxine toxicity. (4)

A meta-analysis of nine published trials involving almost 1,000 women with PMS found that vitamin B6 is more effective in reducing PMS symptoms than placebo. (5)

A double-blind, randomized controlled trial in 94 women found that 80 mg pyridoxine taken daily over the course of three cycles was associated with statistically significant reductions in a broad range of PMS symptoms, including:

• Moodiness
• Irritability
• Forgetfulness
• Bloating
• Anxiety (6)

Below are my preferred dietary sources of Vitamin B6 per 100g:

• Liver – 1mg
• Salmon – 0.9mg
• Sunflower Seeds – 1.33mg
• Pistachios – 1.7mg

The recommended daily allowance sits around 1.3mg, which makes an easy target to obtain via food.

However, to achieve the dosage used in the above studies is between 30-153 times higher than the RDA, making it unachievable to obtain through diet alone.

As you can see here, Designs For Health provides 50mg of Vitamin B6 in just one capsule. This is in the form of Vitamin B6 in its most bioavailable form – P5P.

Magnesium and Vitamin B2 are required for the conversion of P5P. The deficiency rates of magnesium make this conversion much harder.

High protein diets or genetic susceptibilities (such as NBPF3) are factors that can increase the need for more Vitamin B6.

Have you ever used B6 for your PMS?

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References:

1. Goei and Abraham, 1983
2. Brush, 1988
3. Day, 1979
4. London RS, et al. 1991
5. Wyatt KM, et al. BMJ 1999
6. Kashanian M, et al. 2007

How many of the following symptoms for iron deficiency do you have?

• Non-Physical Symptoms
• Anxiety
• Cognitive dysfunction
• Dizziness
• Fatigue
• Headaches
• Lowered attention
• Light-headedness
• Mood swings
• Post-partum depression

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Physical:

• Atrophy or enlargement of the taste buds
• Compromised immune function
• Hair loss
• Koilonychia (Brittle, spoon-shaped nails)
• Leg cramps / heavy legs
• Lowered body temperature
• Mouth sores
• Pale skin complexion
• Palpitations
• Poor thyroid function
• Skin problems
• Shortness of breath
• Swollen tongue
• Restless legs
• Pregnancy complications

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Here are some of the mechanisms behind the above symptoms:

Iron is required for tryptophan hydroxylase activity, this enzyme converts tryptophan to 5HTP, the precursor for serotonin – the chemical brain messenger responsible for our happiness. Therefore with inadequate iron levels, serotonin production will be reduced.

Iron is also needed for tyrosine hydroxylase, this enzyme is essential for the production of dopamine – the chemical brain messenger that is responsible for our drive and motivation.

Iron is essential for the intracellular reception of T3. This reduces the activity of the main thyroid hormone thus lowering metabolism, energy, whilst leading to hair loss and other related factors.

Iron is required to make hemoglobulin. Hemoglobulin helps carry oxygen within the blood to tissues, an integral part of energy production. If iron is low, the body’s ability to produce energy is hindered therefore increasing the likelihood for fatigue. This same mechanism leads to reduced oxygen availability to the brain giving reason as to why headaches are also linked to iron deficiency.

The paling of the skin and inside of the eyelids is due to less hemoglobulin within the blood, as hemoglobulin gives blood its red pigmentation.

Reduced hemoglobulin levels result in less oxygen within the body. As a compensatory mechanism, the body will start to increase breathing and heart rate in hope to get more oxygen, thus leading to a shortness of breath and increased heart palpitations.